Call began his career as a child actor in 1984 appearing in guest roles on Simon & Simon and Hotel. His film debut was voicing "Fairy #1" in Disney's The Black Cauldron in 1985. Also in 1985, he landed a recurring role on the NBC daytime drama, Santa Barbara. During his stint on Santa Barbara, Call earned two Young Artist Awards for the role. After leaving the series in 1987, he guest starred on two episodes of St. Elsewhere, and appeared on the short-lived series The Charmings. From 1989 to 1990, Call portrayed Hobie Buchannon on the first season of Baywatch. Also in 1990, he played Billy in the film Blind Fury. The following year, he starred opposite Andrew Dice Clay in The Adventures of Ford Fairlane and in 1991, appeared in For the Boys starring Bette Midler.
That same year, Call was cast as John Thomas "J.T." Lambert on the ABC sitcom Step by Step, which moved to CBS in 1997. He then regularly appeared as J.T. until the series ended in 1998. After Step by Step ended Call officially left from his acting career to focus on his private life.